Anup has directed a number of open-source projects at IGS and TIGR/JCVI that include PANDA (protein and nucleotide data archive), Workflow, Manatee, Pathema, Gemina, and BRC Central. PANDA is a system built to perform taxonomy based protein clustering used extensively at TIGR/JCVI and IGS to improve microbial and eukaryotic annotation. Workflow is a pipeline execution and management system central to the development of analysis pipelines in use at JCVI, Camera (UCSD), and IGS. This tool has also been deployed at other bioinformatics research institutions worldwide. Some applications have been used extensively in high profile scientific research including the analysis of the Sargasso Sea metagenomic data at TIGR/JCVI. His contributions to web projects such as Pathema and BRC Central include the design and development of a 3-tier architecture that has allowed these tools to be made portable to many different database systems including Sybase, MySQL, and PostgreSQL. He has extensive experience in assembly and closure and helped build TIGR's sequence editing tool Cloe, automated closure tool, AutoCloser, and assembler pipeline CARun. In addition, Anup built TIGR's second-generation laboratory information management system (LIMS), Tracker, and was instrumental in the acquisition and deployment of a LIMS system at IGS.