I want to advance our understanding of the human body, in particular of brain function in health and disorder using non-invasive imaging techniques. To that aim, I pursue the development of methodological tools in signal and image processing to probe into network organization and dynamics, at various stages of the acquisition, processing, and analysis pipeline.

Our main research objective is to develop new methodologies for medical image processing. Most of our projects are related to neuroimaging, including functional magnetic resonance imaging (fMRI), laser Doppler imaging (LDI), and electroencephalography (EEG). Sophisticated tools in signal processing and statistics are required to fully exploit the potential of functional brain imaging data. Among those tools, the wavelet transform receives our particular attention. We develop multivariate analyses based on machine learning techniques that can take advantage of subtle coupling between voxels and lead to backward inference; so-called “mind reading” based on fMRI data. Another research axis pursues better integration of analysis methods for intrinsic and evoked brain activity. Our point-of-view is to consider intrinsic activity as an essential element that modulates evoked activity, for example through fluctuations in brain networks. One of our primary research goals is to bridge the gap between theoretical advances and applications in neurosciences and medical imaging.