My group studies the determinants of skeletal diseases along the life-course (with special focus on osteoporosis), seeking the translation of genomic discoveries into clinical applications. We do this by applying state-of-the art “big data” analytics integrating genomic functional assessments, imaging and other forms of medical data. We have contributed to numerous genomic discoveries in the musculoskeletal field, achieved together with researchers from > 30 countries brought together by the Genetic Factor of Osteoporosis (GEFOS) consortium and the GEnomics of MusculoSkeletal traits TranslatiOnal Network (GEMSTONE-CA-18139) Cost Action.