John G. Laffey - School of Medicine, and Regenerative Medicine Institute (REMEDI), National University of Ireland

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Prediction of PaO2 from SpO2 Values in Critically Ill Invasively Ventilated Patients: Rationale and Protocol for a Patient-Level Analysis of ERICC, LUNG SAFE, PRoVENT and PRoVENT-iMiC (properly II)

Simon Corrado Serafini, David M P van Meenen,Luigi Pisani,Ary Serpa Neto,Luciano César Pontes Azevedo,Tai Pham, Eya Sahraoui,Giacomo Bellani,John G Laffey,Marcus J Schultz,Guido Mazzinari

Critical care science (2025): e20250270-e20250270

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Airway Pressures Generated by High Flow Nasal Cannula in Patients with Acute Hypoxemic Respiratory Failure: A Computational Study

Hossein Shamohammadi,Liam Weaver,Sina Saffaran,Roberto Tonelli,Marianna Laviola,John G. Laffey,Luigi Camporota,Timothy E. Scott,Jonathan G. Hardman,Enrico Clini,Declan G. Bates

Respiratory Researchno. 1 (2025): 1-8

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Impact of Comorbidities on Management and Outcomes of Patients Weaning from Invasive Mechanical Ventilation: Insights from the WEAN SAFE Study

Omid Khazaei, Caoimhe M. Laffey, Rionach Sheerin, Bairbre A. McNicholas,Tài Pham,Leo Heunks,Giacomo Bellani,Laurent Brochard,Andrew J. Simpkin,John G. Laffey

Critical Careno. 1 (2025): 1-13

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Can Nebulised Heparin Reduce Acute Lung Injury in Patients with SARS‑CoV‑2 Requiring Advanced Respiratory Support in Ireland: the CHARTER‑Ireland Phase Ib/IIa, Randomised, Parallel-Group, Open-Label Study

David Cosgrave,Bairbre McNicholas,Ciara Hanley, John Robert Sheehan, Padraig Calpin, Maeve Kernan, Darragh Murphy,Alberto Alvarez‑Iglesias,John Ferguson,Camilla Giacomini, Christine Greene,Catriona Cody, Shane McGeary, Marion Murphy, Marianne Fitzgerald,Gerard Curley,Barry Dixon,Roger J. Smith,Claire Masterson,Daniel O’Toole,Frank van Haren,John G. Laffey

Intensive Care Medicine Experimentalno. 1 (2025): 1-11

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A Randomised, Open-Label Trial of Nebulised Unfractionated Heparin in Patients Mechanically Ventilated for COVID-19

Roger J Smith, Angajendra N Ghosh, Simone Said, Frank Mp van Haren,John G Laffey,Gordon S Doig,John D Santamaria,Barry Dixon

Anaesthesia and intensive carepp.310057X251322783-310057X251322783, (2025)

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Awake Prone Positioning in Adults with COVID-19: an Individual Participant Data Meta-Analysis

Jian Luo,Ivan Pavlov,Elsa Tavernier,Yonatan Perez,Aileen Kharat,Bairbre McNicholas,Oriol Roca,David L Vines, Miguel Ibarra-Estrada,Waleed Alhazzani,Kimberley Lewis,Steven Q Simpson,Garrett Rampon, Ling Liu,Qin Sun,Haibo Qiu,Yi Yang,Giuseppe Lapadula, Edward Tang Qian, Cheryl L Gatto,Todd W Rice, Ken Kuljit S Parhar,Jason Weatherald,Allan J Walkey,Nicholas A Bosch, Mai-Anh Nay,Thierry Boulain,Guillaume Fossat, Tim R E Harris,C Louise Thwaites,Nguyen Thanh Phong,Paolo Bonfanti,Sajad Yarahmadi,Seyed Mohammadreza Hashemian,Devachandran Jayakumar,Stephanie Parks Taylor,Stacy A Johnson,Claude Guerin,John G Laffey,Stephan Ehrmann,Jie Li, Awake Prone Positioning Meta-Analysis Group

JAMA internal medicine（2025）

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Machine Learning Models Compared with Current Clinical Indices to Predict the Outcome of High Flow Nasal Cannula Therapy in Acute Hypoxemic Respiratory Failure

Hang Yu,Sina Saffaran,Roberto Tonelli,John G. Laffey,Antonio M. Esquinas, Lucas Martins de Lima,Letícia Kawano-Dourado,Israel S. Maia,Alexandre Biasi Cavalcanti,Enrico Clini,Declan G. Bates

Critical Careno. 1 (2025): 1-14

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Impact of Frailty and Older Age on Weaning from Invasive Ventilation: a Secondary Analysis of the WEAN SAFE Study

Caoimhe M. Laffey, Rionach Sheerin, Omid Khazaei,Bairbre A. McNicholas,Tài Pham,Leo Heunks,Giacomo Bellani,Laurent Brochard, Dana Tomescu,Andrew J. Simpkin,John G. Laffey

Annals of Intensive Care（2025）

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