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Bio
Prof Jason Mackenzie leads a research team that utilises multidisciplinary approaches to decipher how viruses establish their replicative niche in cells enabling him to construct research programs centred on intracellular virus replication. His background and expertise have resulted in a highly successful program that has culminated in the delivery of 83 research papers cited 8,016x (3,212 citations since 2016) with and average of 96.6 citations/paper; (Google Scholar) with 3 papers recommended in F1000 Prime.
1 of his manuscripts is cited >900x, 2 cited >500x, 1 cited >400x, 3 cited >300x, 5 cited >200x and 10 cited >100x) and the awarding of 9 NHMRC grants as CIA, an additional 2 as CI, and an RO1 NIH grant. Combined this attests to his ability to lead large projects to successful conclusion, including his ability to successfully lead projects where he manage resources, personnel, budget and administrative requirements.
He has a proven expertise in norovirus research: His collaborative discovery of the 1st tissue culture system for norovirus is highly valuable new knowledge that has had significant influence on the field of understanding the determinants of norovirus infection and replication. This significant advance enabled the field to further understand the pathogenesis of norovirus infection, including (i) identifying the intracellular site of norovirus replication and associated ultrastructural changes in cellular membranes ; (ii) roles of the viral proteins during replication; (iii) activation of cellular stress pathways including autophagy and stress granules, modulation of the host translation machinery; (iv) norovirus evasion from both the innate and adaptive arms of the immune system; and (v) the development and assessment of norovirus-specific antivirals. This knowledge would not have been gained if the virus could not be grown in the lab!
1 of his manuscripts is cited >900x, 2 cited >500x, 1 cited >400x, 3 cited >300x, 5 cited >200x and 10 cited >100x) and the awarding of 9 NHMRC grants as CIA, an additional 2 as CI, and an RO1 NIH grant. Combined this attests to his ability to lead large projects to successful conclusion, including his ability to successfully lead projects where he manage resources, personnel, budget and administrative requirements.
He has a proven expertise in norovirus research: His collaborative discovery of the 1st tissue culture system for norovirus is highly valuable new knowledge that has had significant influence on the field of understanding the determinants of norovirus infection and replication. This significant advance enabled the field to further understand the pathogenesis of norovirus infection, including (i) identifying the intracellular site of norovirus replication and associated ultrastructural changes in cellular membranes ; (ii) roles of the viral proteins during replication; (iii) activation of cellular stress pathways including autophagy and stress granules, modulation of the host translation machinery; (iv) norovirus evasion from both the innate and adaptive arms of the immune system; and (v) the development and assessment of norovirus-specific antivirals. This knowledge would not have been gained if the virus could not be grown in the lab!
Research Interests
Papers共 120 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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Linda Earnest,Daniel Fernandez Ruiz,Melissa A. Edeling, Julio M. Carrera, Ashley Huey Yiing Yap,Chinn Yi Wong,Lauren E. Holz,Stephanie Gras,James P. Cooney,Kathryn C. Davidson,Samantha Grimley,Damian Purcell,Jason Roberts, Jamie Mumford,Chee Wah Tan,Lin Fa Wang,Dale Godfrey, Dhiraj Hans,Elizabeth Vincan,Danielle E. Anderson,Kanta Subbarao,Marc Pellegrini,Jason Mackenzie,Steven Rockman,William R. Heath,Joseph Torresi
crossref(2024)
Xiaoxiao Jia,Jeremy Chase Crawford, Deborah Gebregzabher,Ebony A. Monson,Robert C. Mettelman,Yanmin Wan,Yanqin Ren,Janet Chou,Tanya Novak,Hayley A. McQuilten,Michele Clarke,Annabell Bachem, Isabelle J. Foo,Svenja Fritzlar,Julio Carrera Montoya,Alice M. Trenerry,Shuai Nie,Michael G. Leeming,Thi H. O. Nguyen,Lukasz Kedzierski,Dene R. Littler,Andrew Kueh, Tina Cardamone,Chinn Yi Wong,Luca Hensen, Aira Cabug, Jaime Gomez Laguna,Mona Agrawal,Tim Flerlage,David F. Boyd,Lee-Ann Van de Velde,Jennifer R. Habel,Liyen Loh, Hui-Fern Koay,Carolien E. van de Sandt, Igor E. Konstantinov,Stuart P. Berzins,Katie L. Flanagan,Linda M. Wakim,Marco J. Herold,Amanda M. Green,Heather S. Smallwood,Jamie Rossjohn,Ryan S. Thwaites,Christopher Chiu,Nichollas E. Scott,Jason M. Mackenzie,Sammy Bedoui,Patrick C. Reading,Sarah L. Londrigan,Karla J. Helbig,Adrienne G. Randolph,Paul G. Thomas,Jianqing Xu,Zhongfang Wang,Brendon Y. Chua,Katherine Kedzierska
CELLno. 17 (2024)
PLoS Pathogensno. 9 (2024): e1012480-e1012480
Advances in virus research (2024): 1-37
Julio Carrera Montoya,Simon Collett,Daniel Fernandez Ruiz,Linda Earnest,Melissa A. Edeling, Ashley Huey Yiing Yap,Chinn Yi Wong,James P. Cooney,Kathryn C. Davidson,Jason Roberts,Steven Rockman,Bang M. Tran,Julie L. McAuley,Georgia Deliyannis,Samantha L. Grimley,Damian F. J. Purcell,Shafagh A. Waters,Dale I. Godfrey, Dhiraj Hans,Marc Pellegrini,Jason M. Mackenzie,Elizabeth Vincan,William R. Heath,Joseph Torresi
Organoidsno. 1 (2024): 18-31
Catherine W. Y. Wong, Thomas Burton,Julio Carrera Montoya, Nupoor Birje,Xinyi Zhou,Joelle K. Salazar,Jason M. Mackenzie, Thomas F. Rau,Max Teplitski,Wei Zhang
FOODSno. 21 (2024)
Virology (2023): 109969-109969
Virology (2023): 109921-109921
CURRENT PROTOCOLSno. 7 (2023)
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Author Statistics
#Papers: 120
#Citation: 7675
H-Index: 43
G-Index: 87
Sociability: 6
Diversity: 3
Activity: 18
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