She is currently a Tier 2 Canada Research Chair in Hereditary Breast and Ovarian Cancer Prevention.

Dr. Kotsopoulos' research program is dedicated at furthering our understanding of BRCA-associated breast and ovarian cancer with the intent of identifying strategies that confer substantial risk reduction and improve outcome. She also leads several projects aimed at improving our understanding of ovarian cancer heterogeneity and at identifying prognostic factors for this highly fatal disease.