Jonathan A. Pachter - Verastem | 人才画像

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Papers共 169 篇Author StatisticsCo-AuthorSimilar Experts

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FAK Inhibition Combined with the RAF-MEK Clamp Avutometinib Overcomes Resistance to Targeted and Immune Therapies in BRAF V600E Melanoma

Simone Lubrano,Rodolfo Daniel Cervantes-Villagrana,Farhoud Faraji,Sydney Ramirez,Kuniaki Sato, Sendi R Adame-Garcia,Adam Officer,Nadia Arang, Damiano C Rigiracciolo, Paola Y Anguiano Quiroz,Claudia Martini, YiYu Wang,Fleur M Ferguson, Antonietta Bacchiocchi,Ruth Halaban,Silvia Coma,Sheri L Holmen,Jonathan A Pachter,Andrew E Aplin,J Silvio Gutkind

Cancer cell (2025)

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Combined Inhibition of Focal Adhesion Kinase and RAF/MEK Elicits Synergistic Inhibition of Melanoma Growth and Reduces Metastases

Jared Almazan, Tursun Turapov,David A. Kircher, Karly A. Stanley, Katie Culver, A. Paulina Medellin, MiKaela N. Field,Gennie L. Parkman, Howard Colman,Silvia Coma,Jonathan A. Pachter,Sheri L. Holmen

Cell Reports Medicinepp.101943, (2025)

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the SOS1 Inhibitor MRTX0902 Demonstrates Activity Across Cancer Models with Mutations in Proximal Components of the RAS-MAPK Pathway

Niranjan Sudhakar,Larry Yan,Fadia Qiryaqos,Jade laguer,David Briere,Allan Hebbert,Andrew Calinisan,Silvia Coma,Jonathan Pachter,James G. Christensen,Peter Olson,Shilpi Khare

Cancer Research（2024）

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RAMP 205: A Phase 1b/2a Study of Gemcitabine, Nab-Paclitaxel, Avutometinib, and Defactinib in Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Kian-Haut Lim,Manuel Hidalgo,Mark H. O'Hara, Kristen R. Spencer,Ignacio Garrido-Laguna,David G. DeNardo,Vijeta Bhambhani,Gloria Patrick,Yaofeng Cheng,Silvia Coma,Jonathan A. Pachter,Louis J. Denis

CANCER RESEARCHno. 2 (2024)

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Avutometinib/defactinib and Gemcitabine/nab-Paclitaxel Combination in First-Line Metastatic Pancreatic Ductal Adenocarcinoma: Initial Safety and Efficacy of Phase 1b/2 Study (RAMP 205)

Kian-Huat Lim,Kristen Renee Spencer,Rachael A. Safyan,Vincent J. Picozzi,Anna M. Varghese,Despina Siolas,Kimberly Perez, Sheena Clift,Louis J. Denis,Vijeta Bhambhani, Stacey Hill,Jonathan A. Pachter,Philippe Pultar,Manuel Hidalgo

Journal of Clinical Oncologyno. 16_suppl (2024): 4140-4140

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Preclinical Evaluation of Avutometinib and Defactinib in High‐grade Endometrioid Endometrial Cancer

Tobias Max Philipp Hartwich, Miranda Mansolf,Cem Demirkiran,Michelle Greenman,Stefania Bellone,Blair McNamara,Shuvro P. Nandi,Ludmil B. Alexandrov, Yang,Silvia Coma,Jonathan Pachter,Alessandro D. Santin

CANCER MEDICINEno. 17 (2024)

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Abstract A091: the RAF/MEK Clamp Avutometinib As the Backbone of Therapy for Pancreatic Cancer: Novel Combinations with Standard of Care Chemotherapy, FAK Inhibitors, KRAS G12D Inhibitors And/or Autophagy Inhibitors

Silvia Coma,Xiuting Liu,Noah L. Pieper,Wen-Hsuan Chang,Kirsten L. Bryant,Channing J. Der,David G. DeNardo,Jonathan A. Pachter

Cancer Research（2024）

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