Broadly my research is focused on identifying, quantifying, and characterizing the relationships between exposures and genomic variation that modifies susceptibility to complex phenotypes. For the last several years I have explored gene-exposure relationships at a candidate gene and genome wide level in hematological malignancies, prostate and breast cancer, as well as body composition phenotypes. I am PI of Determining the Influence of Susceptibility COnveying VaRiants 1 Year after Bone Marrow Transplant (DISCOVeRY-BMT). Consisting of two cohorts, two genomes and drug-genome interactions, this multi-institutional study of genomic determinants of mortality after unrelated donor BMT has provided many exciting and thought-provoking phenotypic and methodological challenges.