Matteo Castelli - Laboratorio di Microbiologia e Virologia, Università Vita-Salute San Raffaele

基本信息

Career Trajectory

Bio

Organic chemist by formation, currently Postdoctoral researcher in computational chemistry and biochemistry. Experience in computer simulations of biological systems with interest in allosteric mechanism and free energy landscape. Consolidated expertise in integrative structural biology and related drug design applications. Positive attitude to teamwork and advanced communication skills.

Research Interests

Papers共 54 篇Author StatisticsCo-AuthorSimilar Experts

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Disulfide-mediated Tetramerization of TRAP1 Fosters Its Antioxidant and Pro-Neoplastic Activities

Fiorella Faienza,Claudio Laquatra,Matteo Castelli,Salvatore Rizza,Federica Guarra, Azam Roshani Dashtmian,Paola Giglio,Chiara Pecorari,Lavinia Ferrone,Elisabetta Moroni,Francesca Pacello,Andrea Battistoni,Giorgio Colombo,Andrea Rasola,Giuseppe Filomeni

crossref（2024）

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N-Glycosylation-Induced Pathologic Protein Conformations As a Tool to Guide the Selection of Biologically Active Small Molecules

Andrea Magni, Cristiano Sciva,Matteo Castelli,Chander S. Digwal,Anna Rodina,Sahil Sharma,Stefan Ochiana,Hardik J. Patel,Smit Shah,Gabriela Chiosis,Elisabetta Moroni,Giorgio Colombo

CHEMISTRY-A EUROPEAN JOURNAL（2024）

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Structures, Dynamics, Complexes, and Functions: from Classic Computation to Artificial Intelligence

Elena Frasnetti, Andrea Magni,Matteo Castelli,Stefano A. Serapian,Elisabetta Moroni,Giorgio Colombo

CURRENT OPINION IN STRUCTURAL BIOLOGY（2024）

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Single Spike Mutation Differentiating XBB.1 and XBB.1.5 Enhances SARS-CoV-2 Cell-to-cell Transmission and Facilitates Serum-Mediated Enhancement

Elena Criscuolo,Benedetta Giuliani,Matteo Castelli, Mattia Cavallaro,Sofia Sisti,Roberto Burioni,Davide Ferrari,Nicasio Mancini,Massimo Locatelli,Nicola Clementi

FRONTIERS IN IMMUNOLOGY (2024)

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Molecular Mechanisms of Chaperone-Directed Protein Folding: Insights from Atomistic Simulations

Matteo Castelli, Andrea Magni, Giorgio Bonollo,Silvia Pavoni,Francesco Frigerio,A. Sofia F. Oliveira,Fabrizio Cinquini,Stefano A. Serapian,Giorgio Colombo

PROTEIN SCIENCE（2024）

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Unveiling the Role of PUS7-mediated Pseudouridylation in Host Protein Interactions Specific for the SARS-CoV-2 RNA Genome

Roberto Giambruno,Elsa Zacco,Camilla Ugolini,Andrea Vandelli,Logan Mulroney, Manfredi D. ' Onghia, Bianca Giuliani,Elena Criscuolo,Matteo Castelli,Nicola Clementi,Massimo Clementi,Nicasio Mancini,Tiziana Bonaldi,Stefano Gustincich,Tommaso Leonardi,Gian Gaetano Tartaglia,Francesco Nicassio

Molecular Therapy — Nucleic Acids（2023）

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It Takes Two to Tango: Change in the Quaternary Structure and Oncogenicity of TRAP1 Via Cysteine Oxidation

Giuseppe Filomeni,Fiorella Faienza,Claudio Laquatra,Andrea Rasola,Giovanni Chiappetta,Matteo Castelli,Giorgio Colombo,Chiara Pecorari

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERSno. SUPPL 1 (2023): S51-S51

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NLRP3 Monomer Functional Dynamics: from the Effects of Allosteric Binding to Implications for Drug Design

Emanuele Casali,Stefano A. Serapian,Eleonora Gianquinto,Matteo Castelli,Massimo Bertinaria,Francesca Spyrakis,Giorgio Colombo

International Journal of Biological Macromolecules（2023）

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How Aberrant N-glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View

Matteo Castelli,Pengrong Yan,Anna Rodina,Chander S. Digwal,Palak Panchal,Gabriela Chiosis,Elisabetta Moroni,Giorgio Colombo

STRUCTUREno. 8 (2023): 987-+

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PhosY-secretome Profiling Combined with Kinase-Substrate Interaction Screening Defines Active C-Src-driven Extracellular Signaling

Sarah J. Backe,SarahBeth D. Votra,Matthew P. Stokes,Endre Sebestyen,Matteo Castelli,Luca Torielli,Giorgio Colombo,Mark R. Woodford,Mehdi Mollapour,Dimitra Bourboulia

CELL REPORTSno. 6 (2023)

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