Pierre Buekens' research focuses on reproductive epidemiology, including neglected tropical diseases (NTDs) and pregnancy. His current research spans Chagas disease in Argentina, syphilis in the Democratic Republic of the Congo and Zambia, and Zika virus in Honduras. He has worked extensively in Latin America and together with other researchers, he co-founded Trop-G, a collaboration working to control and eliminate NTDs in high-risk areas around the Gulf of Mexico.