His research interests include the development of plasmonic nanostructure, nanocomposites for optical and electrical biosensors, the development of optical imaging system, and wearable devices. These technologies are developed for the applications on cancer diagnosis, noninvasive detection, and neuron transmitters monitoring. He has presided over a number of national scientific research projects, including the National Key Research and Development Project, National Natural Science Foundation of China, Zhejiang Province Natural Science Fund for Distinguished Young Scholars, Zhejiang Province 1000 Talents Plan, Leading Talent Innovation and Entrepreneurship Project of Wenzhou and so on. He is an assistant editor of Light: Science & Aapplications (Nature’s group), an editorial board member of Light Scattering. He has published more than 50 international peer-reviewed paper in Advanced Materials, Chemical Science, Analytical Chemistry, Biosensors and Bioelectronics, Nanoscale and so on, with H index of 28.