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Optimization of 4,6-Bis-anilino-1h-pyrrolo[2,3-d]pyrimidine IGF-1R Tyrosine Kinase Inhibitors Towards JNK Selectivity.

Stanley D. Chamberlain,Aniko M. Redman,Joseph W. Wilson,Felix Deanda,J. Brad Shotwell,Roseanne Gerding,Huangshu Lei,Bin Yang,Kirk L. Stevens,Anne M. Hassell,Lisa M. Shewchuk,M. Anthony Leesnitzer,Jeffery L. Smith,Peter Sabbatini,Charity Atkins,Arthur Groy,Jason L. Rowand,Rakesh Kumar,Robert A. Mook,Ganesh Moorthy,Samarjit Patnaik

Bioorganic & Medicinal Chemistry Letters（2008）

Cited 58|Views54
Key words
IGF-1R,IGF-IR,JNK,Pyrrolopyrimidine
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