Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance

Jeff A. O'Meara,Christopher T. Lemke,Cedrickx Godbout,George Kukolj,Lisette Lagace,Benoit Moreau,Diane Thibeault,Peter W. White,Montse Llinas-Brunet

Journal of Biological Chemistry（2012）

Cited 19|Views20

Key words

Antiviral Agents,Drug Resistance,Hepatitis C Virus,Serine Protease,X-ray Crystallography,Antiviral Resistance,HCV NS3/4A Inhibitor,HCV NS3/4A Protease

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