RYP1 Gene As a Target for Molecular Diagnosis of Histoplasmosis.

Raimunda Sâmia Nogueira Brilhante,Glaucia Morgana de Melo Guedes,Giovanna Barbosa Riello,Joyce Fonteles Ribeiro,Lucas Pereira Alencar,Silviane Praciano Bandeira,Débora Souza Collares Maia Castelo-Branco,Jonathas Sales Oliveira,Janaína Maria Maia Freire,Jacó Ricarte Lima de Mesquita,Zoilo Pires de Camargo,Rossana de Aguiar Cordeiro,Marcos Fábio Gadelha Rocha,José Júlio Costa Sidrim

Journal of microbiological methods（2016）

Cited 5|Views11

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Abstract

This study analyzed the RYP1 gene as a target for the molecular diagnosis of histoplasmosis. This assay detected fungal DNA in 13/13 blood samples from HIV/AIDS-patients with histoplasmosis. Therefore, the detection of RYP1 gene in whole blood sample is a quick and sensitive test to diagnose histoplasmosis.

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