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Genome Organization Drives Chromosome Fragility

Andres Canela,Yaakov Maman,Seolkyoung Jung,Nancy Wong,Elsa Callen,Amanda Day,Kyong-Rim Kieffer-Kwon,Aleksandra Pekowska,Hongliang Zhang,Suhas S. P. Rao,Su-Chen Huang,Peter J. Mckinnon,Peter D. Aplan,Yves Pommier,Erez Lieberman Aiden,Rafael Casellas,Andre Nussenzweig

CELL（2017）

Cited 350|Views132

Key words

DNA breaks,translocations,topologically associated domains,breakpoint cluster regions,topoisomerase,genome instability,cancer,fragile sites

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