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A Fluorine Scan of a Tubulin Polymerization Inhibitor Isocombretastatin A-4: Design, Synthesis, Molecular Modelling, and Biological Evaluation.

Timothee Naret,Jerome Bignon,Guillaume Bernadat,Mohamed Benchekroun,Helene Levaique,Christine Lenoir,Joelle Dubois,Alain Pruvost,Francois Saller,Delphine Borgel,Boris Manoury,Veronique Leblais,Romain Darrigrand,Sebastien Apcher,Jean-Daniel Brion,Etienne Schmitt,Frederic R. Leroux,Mouad Alami,Abdallah Hamze

European Journal of Medicinal Chemistry（2017）

引用 24|浏览40
关键词
isoCA-4,Fluorinated analogs,Cytotoxic,Cancer,Tubulin inhibitors
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