Fragment-based Discovery of a Highly Potent, Orally Bioavailable Inhibitor Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2
Tom D. Heightman,Valerio Berdini,Hannah Braithwaite,Ildiko M. Buck,Megan Cassidy,Juan Castro,Aurelie Courtin,James E. H. Day,Charlotte East,Lynsey Fazal,Brent Graham,Charlotte M. Griffiths-Jones,John F. Lyons,Vanessa Martins,Sandra Muench,Joanne M. Munck,David Norton,Marc O'Reilly,Nick Palmer,Puja Pathuri,Michael Reader,David C. Rees,Sharna J. Rich,Caroline Richardson,Harpreet Saini,Neil T. Thompson,Nicola G. Wallis,Hugh Walton,Nicola E. Wilsher,Alison J. -A. Woolford,Michael Cooke,David Cousin,Stuart Onions,Jonathan Shannon,John Watts,Christopher W. Murray Journal of medicinal chemistry（2018）
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