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Discovery of a Series of 3-Cinnoline Carboxamides As Orally Bioavailable, Highly Potent, and Selective ATM Inhibitors.

Bernard Barlaam,Elaine Cadogan,Andrew Campbell,Nicola Colclough,Allan Dishington,Stephen Durant,Kristin Goldberg,Lorraine A. Hassall,Gareth D. Hughes,Philip A. MacFaul,Thomas M. McGuire,Martin Pass,Anil Patel,Stuart Pearson,Jens Petersen,Kurt G. Pike,Graeme Robb,Natalie Stratton, Guohong Xin,Baochang Zhai

ACS Medicinal Chemistry Letters（2018）

Cited 22|Views61
Key words
ATM,ataxia telangiectasia mutated kinase,PIKK,DDR
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