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BEECH: a Dose-Finding Run-in Followed by a Randomised Phase II Study Assessing the Efficacy of AKT Inhibitor Capivasertib (AZD5363) Combined with Paclitaxel in Patients with Estrogen Receptor-Positive Advanced or Metastatic Breast Cancer, and in a PIK3CA Mutant Sub-Population

N. C. Turner, E. Alarcon,A. C. Armstrong,M. Philco,Y. A. Lopez Chuken,M. -P. Sablin,K. Tamura,A. Gomez Villanueva,J. A. Perez-Fidalgo,S. Y. A. Cheung,C. Corcoran,M. Cullberg, B. R. Davies,E. C. de Bruin,A. Foxley,J. P. O. Lindemann,R. Maudsley,M. Moschetta, E. Outhwaite,M. Pass,P. Rugman,G. Schiavon, M. Oliveira

Annals of Oncology（2019）

Cited 55|Views54
Key words
ER,HER2-,metastatic breast cancer,AKT inhibitor,PIK3CA,capivasertib
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