CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human Ipsc-Derived Neurons

Ruilin Tian,Mariam A. Gachechiladze,Connor H. Ludwig,Matthew T. Laurie,Jason Y. Hong, Diane Nathaniel,Anika V. Prabhu,Michael S. Fernandopulle,Rajan Patel,Mehrnoosh Abshari,Michael E. Ward,Martin Kampmann

Neuron（2019）

引用 233|浏览22

关键词

CRISPR interference,CRISPRi,functional genomics,neuron,stem cell,essential genes,CROP-seq,Perturb-Seq,single-cell RNA sequencing,high-content microscopy

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