Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors Through Cumulative Effects on Individual Targets.
Cell chemical biology(2019)
Key words
polypharmacology,kinase inhibitor,foretinib,cabozantinib,systems pharmacology,chemoproteomics,phosphoproteomics,target selectivity,lung cancer,drug combination
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