Bridging in Vitro Dissolution and in Vivo Exposure for Acalabrutinib. Part I. Mechanistic Modelling of Drug Product Dissolution to Derive a P-PSD for PBPK Model Input
European Journal of Pharmaceutics and Biopharmaceutics（2019）
Key words
Drug product,Dissolution,Mechanistic,Surface pH,Weak base,Prediction,Particle size,PBPK modelling
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