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A Rare Heterozygous TREM2 Coding Variant Identified in Familial Clustering of Dementia Affects an Intrinsically Disordered Protein Region and Function of TREM2

Meliha Karsak,Konstantin Glebov, Marina Scheffold,Thomas Bajaj,Amit Kawalia,Ilker Karaca,Sebastian Rading,Johannes Kornhuber,Oliver Peters,Monica Diez-Fairen,Lutz Froelich,Michael Huell,Jens Wiltfang,Martin Scherer,Steffi Riedel-Heller,Anja Schneider,Michael T. Heneka,Klaus Fliessbach,Ahmed Sharaf,Holger Thiele,Martina Lennarz,Frank Jessen,Wolfgang Maier,Christian Kubisch,Zoya Ignatova,Peter Nuernberg,Pau Pastor,Jochen Walter,Alfredo Ramirez

Human Mutation（2019）

Cited 5|Views60
Key words
Alzheimer disease,conformation,dementia,intrinsically disordered region,TREM2
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