From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Whitney L. Petrilli,Gregory C. Adam,Roman S. Erdmann,Pravien Abeywickrema,Vijayalakshmi Agnani,Xi Ai,Jen Baysarowich,Noel Byrne,John P. Caldwell,Wonsuk Chang,Edward DiNunzio,Zhe Feng,Rachael Ford,Sookhee Ha,Yongcheng Huang,Brian Hubbard,Jennifer M. Johnston,Michael Kavana,Jean-Marie Lisnock,Rui Liang,Jun Lu,Zhijian Lu,Juncai Meng,Peter Orth,Oksana Palyha,Gopal Parthasarathy,Scott P. Salowe,Sujata Sharma,Jennifer Shipman,Stephen M. Soisson,Alison M. Strack,Hyewon Youm,Kake Zhao,Deborah L. Zink,Hratch Zokian,George H. Addona,Karen Akinsanya,James R. Tata,Yusheng Xiong,Jason E. Imbriglio Cell chemical biology(2021)
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Drug Target Identification
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