Design and Characterization of Mouse IgG1 and IgG2a Bispecific Antibodies for Use in Syngeneic Models.

Feng Wang,Jordan C. Tsai,Jonathan H. Davis,Bryant Chau,Jia Dong,Sean M. West,Jason M. Hogan,Matthew L. Wheeler,Christine Bee,Winse Morishige,Thomas Cayton,Donata David-brown,Chengyue Zhang,Alexander Kozhich,Tim Sproul,Gavin Dollinger,Arvind Rajpal,Pavel Strop

mAbs（2019）

Cited 18|Views36

Key words

Mouse bispecific antibodies,electrostatic steering,inter-chain disulfide bond shifting,co-expression,T-cell engaging bispecific antibody,syngeneic mouse model

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