Nucleocytoplasmic Proteomic Analysis Uncovers Erf1 and Nonsense-Mediated Decay As Modifiers of ALS/FTD C9orf72 Toxicity

Juan A. Ortega,Elizabeth L. Daley,Sukhleen Kour,Marisa Samani,Liana Tellez,Haley S. Smith,Elizabeth A. Hall,Y. Taylan Esengul,Yung-Hsu Tsai,Tania F. Gendron,Christopher J. Donnelly,Teepu Siddique,Jeffrey N. Savas,Udai B. Pandey,Evangelos Kiskinis

Neuron（2020）

引用 49|浏览68

关键词

amyotrophic lateral sclerosis,frontotemporal dementia,C9orf72,ETF1/eRF1,nonsense-mediated decay,UPF1,nucleocytoplasmic proteome,nuclear invaginations,motor neurons,neurodegeneration

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