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Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.

Basit Salik,Hangyu Yi,Nunki Hassan,Nancy Santiappillai,Binje Vick,Patrick Connerty,Alastair Duly,Toby Trahair,Andrew J. Woo,Dominik Beck,Tao Liu,Karsten Spiekermann,Irmela Jeremias,Jianlong Wang,Maria Kavallaris,Michelle Haber,Murray D. Norris,Dan A. Liebermann,Richard J. D'Andrea,Christopher Murriel,Jenny Y. Wang

Cancer Cell（2020）

Cited 65|Views109
Key words
AML,acute myeloid leukemia,signaling pathway,WNT/β-catenin,RSPO,LGR4,HOXA9,leukemia stem cells,LSC,self-renewal
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