Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL

Rainer Hubmann,Susanne Schnabl,Mohammad Araghi,Christian Schmidl,Andre F. Rendeiro,Martin Hilgarth,Dita Demirtas, Farghaly Ali,Philipp B. Staber,Peter Valent,Christoph Zielinski,Ulrich Jaeger,Medhat Shehata

Cells（2020）

引用 7|浏览51

关键词

chronic lymphocytic leukemia (CLL),NOTCH2,NOTCH3,FCER2 (CD23),NR4A1,gliotoxin,RO4929097,gamma-secretase inhibitors,ATAC-seq,binary cell fate decision,positive/negative selection,CD5+B-cell homeostasis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要