The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A Study of Crenezumab Versus Placebo in Preclinical PSEN1 E280A Mutation Carriers to Evaluate Efficacy and Safety in the Treatment of Autosomal‐dominant Alzheimer's Disease, Including a Placebo‐treated Noncarrier Cohort

Pierre N. Tariot,Francisco Lopera,Jessica B. Langbaum, Ronald G. Thomas,Suzanne Hendrix, Lon S. Schneider,Silvia Rios-Romenets,Margarita Giraldo,Natalia Acosta,Carlos Tobon,Claudia Ramos,Alejandro Espinosa,William Cho,Michael Ward,David Clayton,Michael Friesenhahn,Howard Mackey,Lee Honigberg,Sandra Sanabria Bohorquez,Kewei Chen

Alzheimer's & Dementia Translational Research & Clinical Interventions（2018）

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Key words

Alzheimer's disease,Autosomal-dominant Alzheimer's disease,Preclinical Alzheimer's disease,Prevention,Clinical trial,Crenezumab,Alzheimer's Prevention Initiative

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