Derivation of a Dynamic Model for Palmitate-induced NFκB Signaling Pathway Through Systems Biology Approach
2020 AMERICAN CONTROL CONFERENCE (ACC)（2020）
Key words
trained model,model predictions,key molecules,palmitate-induced TNFα expression,comprehensive dynamic model,AMPK activity,ordinary differential equations,representative FFA,TNFα synthesis,FFA-induced inflammation,detailed mechanisms,inflammatory response,tumor necrosis factor-α,pro-inflammatory cytokines,elevated level,monophosphate-activated protein kinase activity,chronic inflammation,FFAs,free fatty acids,chronic diseases,causal link,public health,severe threat,obesity,systems biology approach,palmitate-induced NFκB signaling pathway
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