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PHYSIOLOGICALLY-BASED PHARMACOKINETIC AND CLINICAL STUDY TO ASSESS EFFECTS OF CYP3A INDUCTION AND INHIBITION ON COPANLISIB PK IN CANCER PATIENTS.

J. -F. Schlender,J. Grevel, S. Frechen, C. Diedrich,R. Burghaus,A. Spreafico,M. Sawyer,L. L. Siu,F. Huang,S. Reschke, C. Xia, Z. Yan,I. Genvresse,G. Cisternas,A. Kelly,S. Reif,C. Granvil

CLINICAL PHARMACOLOGY & THERAPEUTICS（2019）

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