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Trem2 Restrains the Enhancement of Tau Accumulation and Neurodegeneration by Β-Amyloid Pathology

Seung-Hye Lee,William J. Meilandt,Luke Xie,Vineela D. Gandham,Hai Ngu,Kai H. Barck,Mitchell G. Rezzonico,Jose Imperio,Guita Lalehzadeh,Melanie A. Huntley,Kimberly L. Stark,Oded Foreman,Richard A. D. Carano,Brad A. Friedman,Morgan Sheng,Amy Easton,Christopher J. Bohlen,David V. Hansen

Neuron（2021）

引用 117|浏览47
关键词
Alzheimer’s disease,TREM2,microglia,tauopathy,neurodegeneration,gliosis,neuroinflammation,single-cell RNA sequencing,MRI,disease-associated microglia
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