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Reconstructing Single-Cell Karyotype Alterations in Colorectal Cancer Identifies Punctuated and Gradual Diversification Patterns.

Yannik Bollen,Ellen Stelloo,Petra van Leenen,Myrna van den Bos,Bas Ponsioen,Bingxin Lu,Markus J. van Roosmalen,Ana C. F. Bolhaqueiro,Christopher Kimberley,Maximilian Mossner,William C. H. Cross,Nicolle J. M. Besselink,Bastiaan van der Roest,Sander Boymans,Koen C. Oost,Sippe G. de Vries,Holger Rehmann,Edwin Cuppen,Susanne M. A. Lens,Geert J. P. L. Kops,Wigard P. Kloosterman,Leon W. M. M. Terstappen,Chris P. Barnes,Andrea Sottoriva,Trevor A. Graham,Hugo J. G. Snippert

Nature Genetics（2021）

Cited 28|Views58
Key words
Colorectal cancer,DNA sequencing,Time-lapse imaging,Biomedicine,general,Human Genetics,Cancer Research,Agriculture,Gene Function,Animal Genetics and Genomics
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