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Splicing Factor Proline and Glutamine Rich Intron Retention, Reduced Expression and Aggregate Formation Are Pathological Features of Amyotrophic Lateral Sclerosis

Alison L. Hogan,Natalie Grima,Jennifer A. Fifita,Emily P. McCann,Benjamin Heng,Sandrine Chan Moi Fat,Sharlynn Wu,Ram Maharjan,Amy K. Cain,Lyndal Henden,Stephanie Rayner,Ingrid Tarr,Katharine Y. Zhang,Qiongyi Zhao,Zong-Hong Zhang,Amanda Wright,Albert Lee,Marco Morsch,Shu Yang,Kelly L. Williams,Ian P. Blair

Neuropathology and Applied Neurobiology（2021）

Cited 9|Views47
Key words
amyotrophic lateral sclerosis,histopathology,polypyrimidine tract-binding protein-associated splicing factor (PSF),protein aggregation,RNA expression,RNA processing,splicing factor proline and glutamine rich (SFPQ)
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