Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer's Disease.

Gilbert M. Rishton,Gary C. Look,Zhi-Jie Ni, Jason Zhang, Yingcai Wang,Yaodong Huang,Xiaodong Wu,Nicholas J. Izzo,Kelsie M. LaBarbera,Colleen S. Limegrover,Courtney Rehak,Raymond Yurko,Susan M. Catalano

ACS Medicinal Chemistry Letters（2021）

引用 19|浏览18

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CT1812,amyloid oligomer,amyloid oligomer-displacing,A beta O,A beta O-displacing,Alzheimer's disease drug,sigma-2,transmembrane protein 97,TMEM97,progesterone receptor membrane component 1,PGRMC1,supercritical fluid extraction,SFE,conditioned extraction,CE

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