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HIV Broadly Neutralizing Antibodies Expressed As IgG3 Preserve Neutralization Potency and Show Improved Fc Effector Function

Simone I. I. Richardson,Frances Ayres,Nelia P. P. Manamela,Brent Oosthuysen,Zanele Makhado,Bronwen E. E. Lambson,Lynn Morris,Penny L. L. Moore

Frontiers in Immunology（2021）

Cited 12|Views20
Key words
broadly neutralizing antibodies (bnAbs),Fc effector function,IgG3,phagocytosis,ADCC (antibody dependent cellular cytotoxicity)
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