Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange
Tom Dixon,Derek MacPherson,Barmak Mostofian,Taras Dauzhenka,Samuel Lotz,Dwight McGee,Sharon Shechter,Utsab R. Shrestha,Rafal Wiewiora,Zachary A. McDargh,Fen Pei,Rajat Pal,João V. Ribeiro,Tanner Wilkerson,Vipin Sachdeva,Ning Gao,Shourya Jain,Samuel Sparks,Yunxing Li,Alexander Vinitsky, Xin Zhang,Asghar M. Razavi,István Kolossváry,Jason Imbriglio,Artem Evdokimov,Louise Bergeron,Wenchang Zhou,Jagat Adhikari,Benjamin Ruprecht,Alex Dickson,Huafeng Xu,Woody Sherman,Jesus A. Izaguirre bioRxiv(2021)
Key words
Cereblon-Dependent Degradation
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