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Epstein Barr Virus–positive B-cell Lymphoma is Highly Vulnerable to MDM2 Inhibitors in Vivo

Xiaoshan Zhang,Ran Zhang,Chenghui Ren,Yi Xu,Shuhong Wu,Carrie Meng,Apar Pataer,Xingzhi Song,Jianhua Zhang,Yixin Yao,Hua He,Huiqin Chen,Wencai Ma,Jing Wang,Funda Meric-Bernstam,Richard E. Champlin,John Heymach,Cliona M. Rooney,Stephen G. Swisher,Ara A. Vaporciyan,Jack A. Roth,M. James You,Michael Wang,Bingliang Fang

Blood Advances（2021）

Cited 4|Views57
Key words
MDM2 inhibitors have potent in vivo activity against and could be a novel therapy for EBV-positive B-cell lymphoma,EBV positivity or loss of BCL6 expression can be a potential predictive biomarker for response to MDM2 inhibitors in patients with lymphoma
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