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Ipsc-Induced Neurons with the V337M MAPT Mutation Are Selectively Vulnerable to Caspase-Mediated Cleavage of Tau and Apoptotic Cell Death

Panos Theofilas,Chao Wang,David Butler,Dulce O. Morales,Cathrine Petersen,Andrew Ambrose,Brian Chin,Teddy Yang,Shireen Khan,Raymond Ng,Rakez Kayed,Celeste M. Karch,Bruce L. Miller,Jason E. Gestwicki,Li Gan,Sally Temple,Michelle R. Arkin,Lea T. Grinberg

Molecular and Cellular Neuroscience（2024）

引用 0|浏览18
关键词
Tau cleavage,Neoepitope antibody,Active caspase-6,iPSCs,FTLD,V337M MAPT mutation,Tauopathies,Postmortem
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