Deriving Waveform Parameters from Calcium Transients in Human Ipsc-Derived Cardiomyocytes to Predict Cardiac Activity with Machine Learning.

Hongbin Yang,Will Stebbeds,Jo Francis,Amy Pointon,Olga Obrezanova,Kylie A. Beattie,Peter Clements,James S. Harvey,Graham F. Smith,Andreas Bender

Stem Cell Reports（2022）

Cited 8|Views22

Key words

cardiotoxicity,machine learning,hiPSC-CMs,calcium transients,cardiac activity,waveform parameters,random forest,cardiovascular liability,cardiomyocytes

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