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De Novo Generation of the NPM-ALK Fusion Recapitulates the Pleiotropic Phenotypes of ALK+ ALCL Pathogenesis and Reveals the ROR2 Receptor As Target for Tumor Cells

Babin Loélia, Darchen Alice,Robert Elie,Aid Zakia, Borry Rosalie,Soudais Claire,Piganeau Marion,De Cian Anne,Giovannangeli Carine,Bawa Olivia,Rigaud Charlotte,Scoazec Jean-Yves,Couronné Lucile,Veleanu Layla,Cieslak Agata,Asnafi Vahid,Sibon David,Lamant Laurence,Meggetto Fabienne,Mercher Thomas,Brunet Erika

Molecular Cancer（2022）

引用 2|浏览41
关键词
ALK+ ALCL,Lymphoma,NPM-ALK fusion,CRISPR/Cas9 models,WNT,ROR2,Biomarker,Therapeutic targets
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