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Safety and Tolerability of AAV8 Delivery of a Broadly Neutralizing Antibody in Adults Living with HIV: a Phase 1, Dose-Escalation Trial

Joseph P. Casazza,Evan M. Cale,Sandeep Narpala,Galina V. Yamshchikov,Emily E. Coates,Cynthia S. Hendel,Laura Novik,LaSonji A. Holman,Alicia T. Widge,Preeti Apte,Ingelise Gordon,Martin R. Gaudinski,Michelle Conan-Cibotti,Bob C. Lin,Martha C. Nason,Olga Trofymenko,Shinyi Telscher,Sarah H. Plummer,Diane Wycuff,William C. Adams,Janardan P. Pandey,Adrian McDermott,Mario Roederer, Avery N. Sukienik,Sijy O’Dell,Jason G. Gall,Britta Flach,Travis L. Terry,Misook Choe,Wei Shi,Xuejun Chen,Florence Kaltovich,Kevin O. Saunders,Judy A. Stein,Nicole A. Doria-Rose,Richard M. Schwartz,Alejandro B. Balazs,David Baltimore,Gary J. Nabel,Richard A. Koup,Barney S. Graham,Julie E. Ledgerwood,John R. Mascola,Charla Andrews

Nature Medicine（2022）

Cited 29|Views77
Key words
Applied immunology,Genetic vectors,Phase I trials,Translational research,Biomedicine,general,Cancer Research,Metabolic Diseases,Infectious Diseases,Molecular Medicine,Neurosciences
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