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Efficient Spontaneous Site-Selective Cysteine-Mediated Toxin Attachment Within a Structural Loop of Antibodies

Gerhard Stadlmayr,Florian Stracke,Katharina Stadlbauer,Jakub Rybka,Stephan Dickgiesser,Nicolas Rasche,Stefan Becker,Lars Toleikis,Florian Rueker,Gordana Wozniak Knopp

Biochimica et Biophysica Acta (BBA) - General Subjects（2022）

Cited 1|Views15
Key words
Antibody-drug conjugates,Conjugation efficiency,Engineered cysteine,Site-specific coupling,Pi-clamp mutagenesis
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