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CRISPR/Cas9-mediated Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Prevents Obesity and Cardiac Ischemic Injury

Matthieu Leuillier,Thomas Duflot,Severine Menoret,Hind Messaoudi,Zoubir Djerada,Deborah Groussard,Raphael G. P. Denis,Laurence Chevalier,Ahmed Karoui,Baptiste Panthu,Pierre-Alain Thiebaut,Isabelle Schmitz-Afonso,Severine Nobis, Cynthia Campart,Tiphaine Henry,Camille Sautreuil,Serge H. Luquet,Olivia Beseme,Catherine Feliu,Helene Peyret,Lionel Nicol,Jean-Paul Henry,Sylvanie Renet,Paul Mulder,Debin Wan,Laurent Tesson,Jean-Marie Heslan,Angeline Duche,Sebastien Jacques,Frederic Ziegler,Valery Brunel,Gilles J. P. Rautureau,Christelle Monteil,Jean-Luc do Rego,Jean-Claude do Rego,Carlos Afonso,Bruce Hammock,Anne-Marie Madec, Florence Pinet,Vincent Richard,Ignacio Anegon,Christophe Guignabert,Christophe Morisseau,Jeremy Bellien

JOURNAL OF ADVANCED RESEARCH（2023）

Cited 8|Views46
Key words
Soluble epoxide hydrolase,Lipid phosphatase,CRISPR-Cas9,Thermogenesis,Obesity,Cardiac ischemic injury
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