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GSDMB is Increased in IBD and Regulates Epithelial Restitution/repair Independent of Pyroptosis

Nitish Rana,Giuseppe Privitera,Hannah C. Kondolf,Katarzyna Bulek,Susana Lechuga,Carlo De Salvo,Daniele Corridoni,Agne Antanaviciute,Rebecca L. Maywald,Alexander M. Hurtado,Junjie Zhao,Emina H. Huang,Xiaoxia Li,E. Ricky Chan,Alison Simmons,Giorgos Bamias,Derek W. Abbott,Jason D. Heaney,Andrei I. Ivanov,Theresa T. Pizarro

Cell（2024）

Cited 90|Views9
Key words
gasdermins,gasdermin B,GSDMB,inflammatory bowel disease,intestinal epithelial cells,epithelial organoids,single-cell profiling,single-cell RNA-seq,GSDMB genetic polymorphisms,methotrexate,Mtx,platelet-derived growth factor A,PDGFA,focal adhesion kinase,FAK,epithelial restitution and repair,resolution of inflammation
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