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Clostridium Butyricum Therapy Restores the Decreased Efficacy of Immune Checkpoint Blockade in Lung Cancer Patients Receiving Proton Pump Inhibitors

Yusuke Tomita,Yoshihiko Goto,Shinya Sakata,Kosuke Imamura,Ayaka Minemura,Kentaro Oka,Atsushi Hayashi,Takayuki Jodai,Kimitaka Akaike,Moriyasu Anai,Shohei Hamada,Shinji Iyama,Koichi Saruwatari,Sho Saeki,Motomichi Takahashi,Tokunori Ikeda,Takuro Sakagami

OncoImmunology（2022）

Cited 30|Views28
Key words
Antibiotics,CBM588,gut microbiome,immune checkpoint blockade,clostridium butyricum,lung cancer,oral microbiota,proton pump inhibitors (PPIs)
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