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Safety and Immunogenicity of an HIV-1 Prefusion-Stabilized Envelope Trimer (trimer 4571) Vaccine in Healthy Adults: A First-in-human Open-Label, Randomized, Dose-Escalation, Phase 1 Clinical Trial

Katherine Houser,Martin R. Gaudinski,Myra Happe,Sandeep Narpala,Raffaello Verardi,Edward K. Sarfo,Angela R. Corrigan,Richard Wu,Ro Shauna Rothwell,Laura Novik,Cynthia S. Hendel,Ingelise J. Gordon,Nina M. Berkowitz, Cora Trelles Cartagena,Alicia T. Widge,Emily E. Coates,Larisa Strom,Somia Hickman,Michelle Conan-Cibotti,Sandra Vazquez,Olga Trofymenko,Sarah Plummer,Judy Stein,Christopher L. Case,Martha Nason,Andrea Biju,Danealle K. Parchment,Anita Changela, Cheng,Hongying Duan,Hui Geng,I-Ting Teng,Tongqing Zhou,Sarah O'Connell, Chris Barry,Kevin Carlton,Jason G. Gall,Britta Flach,Nicole A. Doria-Rose,Barney S. Graham,Richard A. Koup,Adrian B. McDermott,John R. Mascola,Peter D. Kwong,Julie E. Ledgerwood

EClinicalMedicine（2022）

Cited 13|Views75
Key words
HIV-1,Vaccine,Trimer 4571,BG505 DS-SOSIP.664,Phase 1 clinical trial,NIH
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