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Potent Broadly Neutralizing Antibody VIR-3434 Controls Hepatitis B and D Virus Infection and Reduces HBsAg in Humanized Mice.

Florian A. Lempp,Tassilo Volz,Elisabetta Cameroni,Fabio Benigni,Jiayi Zhou,Laura E. Rosen,Julia Noack,Fabrizia Zatta,Hannah Kaiser,Siro Bianchi,Gloria Lombardo,Stefano Jaconi,Lucia Vincenzetti,Hasan Imam,Leah B. Soriaga,Nadia Passini,David M. Belnap,Andreas Schulze,Marc Luetgehetmann,Amalio Telenti,Andrea L. Cathcart,Gyorgy Snell,Lisa A. Purcell,Christy M. Hebner,Stephan Urban,Maura Dandri,Davide Corti,Michael A. Schmid

Journal of Hepatology（2023）

Cited 9|Views70
Key words
Hepatitis B virus (HBV),Hepatitis delta virus (HDV),chronic infection,neutralization,monoclonal antibody (mAb),HBsAg,anti-HBs,human liver chimeric mice,virus spread
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