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Molecular Interactions of PCSK9 with an Inhibitory Nanobody, CAP1 and HLA-C: Functional Regulation of LDLR Levels

Carole Fruchart Gaillard,Ali Ben Djoudi Ouadda,Lidia Ciccone,Emmanuelle Girard,Sepideh Mikaeeli,Alexandra Evagelidis,Mailys Le Devehat,Delia Susan-Resiga, Evelyne Cassar Lajeunesse,Herve Nozach,Oscar Henrique Pereira Ramos,Aurelien Thureau,Pierre Legrand,Annik Prat,Vincent Dive,Nabil G. Seidah

MOLECULAR METABOLISM（2023）

Cited 2|Views36
Key words
Crystal structures,PCSK9 induced LDLR degradation,Single domain antibody inhibition,CAP1 enhancer,Role of CHRD,HLA-C
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