Computational Quantification and Characterization of Independently Evolving Cellular Subpopulations Within Tumors is Critical to Inhibit Anti-Cancer Therapy Resistance

Heba Alkhatib,Ariel M. Rubinstein,Swetha Vasudevan,Efrat Flashner-Abramson,Shira Stefansky,Sangita Roy Chowdhury,Solomon Oguche,Tamar Peretz-Yablonsky,Avital Granit,Zvi Granot,Ittai Ben-Porath,Kim Sheva,Jon Feldman,Noa E. Cohen,Amichay Meirovitz,Nataly Kravchenko-Balasha

Genome Medicine（2022）

引用 7|浏览30

关键词

Cancer resistance,Intra-tumor heterogeneity,Tumor plasticity,Information-theoretic single-cell analysis,Individualized targeted therapy,Radiation oncology,Triple-negative breast cancer

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